Dental caries is an imbalance between the gain and loss of minerals. The minerals are lost from teeth by acids produced by bacteria within the mouth whereas minerals are gained from saliva and fluorides present in the oral cavity. Posterior teeth have fissures while anterior teeth have cingulum or pits. These pits and fissure are most prone to dental decay as food gets trapped in them and are difficult to clean. Pit and fissure sealants are material used to fill these pits and fissures to create a smooth surface making it easy to clean. Pit and fissure sealants are commonly used in pediatric patients and erupting permanent molars as they are at high risk. Pit and fissure sealants are a preventive treatment method where a barrier is created and removes biofilm from the occlusal surface. This library dissertation highlights various pit and fissure sealants, their indication, contraindication, technique of application.